Brake F16 recently received full registration for use on cotton. It is a mixture of fluridone and fomesafen (fomesafen is the active ingredient in Reflex). Brake F16 was available under a Section 18 Exemption in 2015, and Brake F2 (different ratio of active ingredients) was available under Section 18 in 2014.
At the typical use rate of 1 pt per acre, Brake F16 gives 0.15 lb ai of fluridone and 0.1875 lb ai of fomesafen (equivalent to 12 oz of Reflex). The current label claims control only of pigweed species, but Brake F16 has pretty good activity on annual grasses and most small-seeded broadleaf weeds.
Most North Carolina research with Brake F16 has focused on Palmer amaranth. Control has been as good as or sometimes a little better than with our commonly used preemergence combinations. Cotton tolerance has been good. Brake F16 is not a stand-alone product. One needs to follow Brake with a normal, timely postemergence program.